Our Services
|
CellAura offers a contract fluorescent reagent development and validation service. We can design, synthesize and provide a full pharmacological characterisation of the product you require. A typical custom reagent development programme comprises a synthesis of a 'first round' reagent mini-library – using a pharmacologically defined 'warhead' and a fluorescent label, joined with a selection of linker chemistries. Following pharmacological evaluation of the 'first round' mini-library [either by CellAura using cell-based binding assays or by the customer using in-house assay(s)], an active reagent is further optimised in a 'second round' mini-library to suit the customer's application. After selection of the final product from the 'second round' mini-library, a specified quantity is provided to the customer, with re-order of the product as required. Through its unique approach to chemical synthesis, CellAura has developed a number of bespoke fluorescent GPCR ligands to meet customer requirements for use with a range of fluorescence imaging / drug screening / pharmacological techniques.
|
 |