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Reagent Details

Adenosine family

Catalogue number: CA200623
Product: Adenosine agonist [NECA]
Selectivity: A1: 8.47 | A2a: 6.76 | A2b: 5.69 | A3: 8.57

Pharmacophore   Adenosine-5’-N-ethyluronamide (NECA)-derivative
Molecular Weight   925
Purity   ≥97%
Excitation   638 nm
Emission   657 nm

 

Applications

For ligand binding, fluorescence imaging and high content analysis, kinetic analysis and cell sorting at adenosine A1 / A2A / A3 receptors use solutions up to 100 nM.

Pharmacological Validation

For full experimental details see:
• J. Med. Chem. 2007, 50, 782-793
• FASEB J. 2008, 22, 850-860

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